Associate Professor

Chen, Chien-Ho, Ph.. D.
TEL886-27361661 #3320

Highest Degree
Ph.D. Pharmaceutical Science, Taipei Medical College, Taipei, Taiwan

Arthritis research
Original paper: ( since 2002 )
01. Ying-Jan Wang, Jiiang-Huei Jeng, Rong-Jane Chen, How Tseng, Li-Ching Chen, Yu-Chin Liang, Chien-Huang Lin, Chien-Ho Chen , Jan-Show Chu, Wei-Lu Ho, and Yuan-Soon Ho (Correspondence). (2002) Ketoconazole potentiate the antitummor effects of nocodazole: in vivo therapy of human tumor xenografits in nud mice. Molecular Carcinogenesis 34(4):199-210
02. Ying-Jan Wang, Chen-Fei Yu, Li-Ching Chen, Chien-Ho Chen , Jen-Kun Lin, Yu-Chin Liang, Chien-Huang Lin, Shyr-Yi Lin, Chin-Fa Chen, and Yuan-Soon Ho (Correspondence). (2002) Ketoconazole potentiate terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 actiaity. Journal of Cellular Biochemistry 87:147-159
03. Chia-Jen Tseng, Ying-Jan Wang, Yu-Chin Liang, Jiiang-Huei Jeng, Wen-Sen Lee, Jen-Ken Lin, Chien-Ho Chen , I-Chun Liu, and Yuan-Soon Ho (Correspondence). (2002) Microtubule damaging agents induce apoptosis in HL 60 cell and G2/M cell cycle arrest in HT 29 cell through independent signaling pathway. Toxicology 175:123-142
04. Chin-Hsiung Wu, Jiiang-Huei Jeng, Ying-Jan Wang, Chia-Jen Tseng, Yu-Chin Liang, Chien-Ho Chen , Horng-Mo Lee, Jen-Kun Lin, Chien-Huang Lin, Shyr-Yi Lin, Chung-Pei Li, and Yuan-Soon Ho (Correspondence). (2002) Antitummur effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest. Toxicology and Applied Pharmacology 180: 22-35
05. Chien-Ho Chen , Ling-Fang Huang, Li-Ching Chen, and Yuan-Soon Ho. (2002) Ketoconazole induces apoptosis through induction of Bax-signaling pathway in human prostate cancer cell lines. New Taipei Journal of Medicin e 4: 159-166
06. Chen CH , Chen TF, Chen HY, Lin SC, Chen PL, and Wu CH. Protective effect of rhGM-CSF against Candida Allcans infection in immunosuppressed mice. (2002) New Teipei Journal of Medicine 17:55-64.
07. Hung CH, Chen LC, Zhang Z, Chowdhury B, Lee WL, Plunkett B, Chen CH , Myers AC and Huang SK. (2004) Regulation of TH2 responses by the pulmonary Clara cell secretory 10-kd protein. J Allergy Clin Immunol. 114: 664-670.
08. Gao PS, Heller NM, Walker W, Chen CH , Plunkett B, Roberts MH, Schleimer RP, Hopkin JM and Huang SK. (2004) Variation in dinucleotide (GT) repeat sequence in the first exon of the STAT6 gene is associated with atopic asthma and differentially regulates the promoter activity in vitro. J Med Genet. 41:535-539.
09. Ho YS, Wu CH, Chen CH , Wang YJ, Pestell RG, Albanese C, Chen RJ, Chang MC, Jeng JH, Lin SY (2004) Tobacco specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal bronchial epithelial cells through NFkB activation and cyclin D1 upregulation. Tox Appl Pharmacol, In press.
10. Hsu YH, Hsieh MS, Liang YC, Li CY, Sheu MT, Chou DT, Chen TZ, Chen CH (2004) Production of The Chemokine Eotaxin-1 in Osteoarthritis and Its Role in Cartilage Degradation. J Cell Biochemistry, 93: 929-939.
11. Chou YH, Ho FM, Liu DZ, Lin SY, Tsai LH, Chen CH , Ho YS, Hung LF, Liang YC (2005) The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1. Inter J Biochem Cell Biol., 37: 604–615.
12. Chen CH, Sheu MT, Lin KP, Ho HO(2006).Stimultaneous effects of tocopheryl polyethylene glycol; succinate on local hair growth promotion and systemic absorption of topically applied minoxidil in a mouse model. International journal of pharmaceutics.(306):91-98. 
13. Chen CH, Sheu MT, Chen TF, Wang YC, Hou WC, Liu DZ. Chung TC. Liang YC(2006).Suppression of endotonion-induced proinflammatory responses by citrus pectin through blocking LPS signaling pathways. Biochemical Pharmacology.(72):1001-1009. 
14. Lu HT, Liang YC, Sheu MT, Ho HO, Lin YT, Hsieh MS, Chen CH(2007).Disease-Modifying Effects of Glucosamine HCL Involving Regulation of Metallopproteinases and Chemokines Activated by Interleukin-ib in Human Primary Synovial Fibroblasts. J of Cellular Biochemistry.():-. 
15. Lo YJ, Sheu MT, Tsai WC, Lin YH, Li JL, Liang YC, Chang CC, Hsieh MS, Chen CH(2007).Intra-articular injection of hyaluronate andindomethacin in rabbits with antigen-induced arthritis. Rheumatology International.():-.


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