Associate Professor
　 　

Shu-Huei Kao, Ph. D.
TEL：886-27361661 #3317
E-mail：kaosh@tmu.edu.tw
　

Highest Degree
　 　
Doctor of Philosophy

Specialties
　
Reproductive medicine
Mitochondrial medicine
　
Original paper： ( since 1997 )
　
01.

Liu, C.S., Yip, P.K., Kao, S.H. , and Wei, Y.H. (1997) Simultaneous declined of Mn-SOD and increase of lipid peroxidation in brain mitochondria following ischemia-reperfusion. Biochem. Mol. Biol. Biophys. 1, 95-102.  ( SCI )
02. Liu, C.S., Kao, S.H. , and Wei, Y.H. (1997) Smoking-associated mitochondrial DNA mutations in human hair follicles. Environ. Mol. Mutagen. 30, 47-55.  ( SCI )
03. Liu, C.S., Wu, H.M., Kao, S.H. , and Wei, Y.H. (1997) Phenotoin-mediated oxidative hydantoin syndrome. Human Exp. Toxicol. 16, 177-181.  ( SCI )
04. Liu, C.S., Wu, H.M., Kao, S.H. , and Wei, Y.H. (1998) Serum trqace elements, glutathione, Cu,Zn-superoxide dismutase, and lipid peroxidation in epileptic patients with phenytoin or carbamazepine monotherapy. Clin. Neuropharma. 21, 62-64.  ( SCI )
05. Kao, S.H. , Chao, H.T., and Wei, Y.H. (1995) Mitochondrial deoxyribonucleic acid 4977-bp deletions is associated with the decline of fertility and motility of human sperm. Biol. Reprod. 52, 285-298  ( SCI )
06. Kao, S.H. , Liu, C.S., Wang, S.Y., and Wei, Y.H. (1997) Ageing-associated large-scale deletions of mitochondrial DNA in hair follicles. Biochem. Mol. Biol. Int. 42, 285-298.  ( SCI )
07. Fahn, H.J., Wang, L.S., Chang, S.C., Kao, S.H. , Haung, M.H., and Wei, Y.H. (1998) Smoking-associated mitochondrial DNA mutations and lipid peroxidation in human lung tissue. Am. J. Respir. Cell Mol. Biol.,19, 901-909.  ( SCI )
08. Kao, S.H. , Chao, H.T., and Wei, Y.H. (1998) Multiple deletions of mtDNA are associated with the decline of fertility and motility of human sperm. Mol. Hum. Reprod. 4,657-666.  ( SCI )
09. Wei, Y.H., and Kao, S.H. (2000) Mitochondrial DNA Mutation and Depletion are associated with the decline of fertility and motility of human sperm. Zoological Studies 39, 1-12.  ( SCI )
10. Liu, L.S., Ko, L.Y., Lim, P.S., Kao, S.H. , Wei, Y.H. (2001) Biomarkers of DNA damage in patients with end-stage renal disease: mitochondrial DNA mutation in hair follicles. Nephrol Dial Transplan, 16(3):561-5.  ( SCI )
11.  Rovio, A.T., Marchington, D.R., Donat, S., Schuppe, HC, Abel, J., Fritsche, E., Elliott, D.J., Laippala, P., Ahola, A.L., McNay, D., Harrison, R.F., Hughes, B., Barrett, T., Bailey, D.M.D., Mehmet, D., Jequier, A.M., Hargreave, T.B., Kao, S.H. , Cummins, J.M., Barton, D.E., Cooke, H.J., Wei, Y.H., Wichmann, L., Poulton, J., and Jacobs, H.T. (2001) Mutations at the mitochondrial DNA polymerase ( POLG ) locus associated with male infertility. Nature Genetics, 29(3):261-2.  ( SCI )
12. Wang Y. C., Kao, S.H. , Hsieh, H.J. (2003) A chemical surface modification of chitosan by glycoconjugates to enhance the cell-biomaterial interaction. Biomacromolecules , 4, 224 - 231
13. Yen MY, Kao SH, Wang AG, Wei YH. (2004) Increased 8-hydroxy-2'- deoxyguanosine in leukocyte DNA in Leber's hereditary optic neuropathy. Invest Ophthalmol Vis Sci.,45,1688-1691.
14. Rovio AT, Abel J, Ahola AL, Andres AM, Bertranpetit J, Blancher A, Bontrop RE, Chemnick LG, Cooke HJ, Cummins JM, Davis HA, Elliott DJ, Fritsche E, Hargreave TB, Hoffman SM, Jequier AM, Kao SH , Kim HS, Marchington DR, Mehmet D, Otting N, Poulton J, Ryder OA, Schuppe HC, Takenaka O, Wei YH, Wichmann L, Jacobs HT. (2004) A prevalent POLG CAG microsatellite length allele in humans and African great apes. Mamm Genome. 15, 492-502.
15. Kao, S.H. , Chao, H.T., Liu, H.W., Liao, T.L., and and Wei, Y.H. (2004) Mitochondrial DNA depletion in the male with asthenospermia. Fertil Steril, 82, 66-73.
16. Au HK, Yeh, TS, Kao SH , Tzeng CR, Hsieh RH. Abnormal mitochondrial structure in human unfertilized oocytes and arrested embryos. Annals NY Acad Sci (in press).
17. Hou, C.C., Hung, S. L., Kao, S.H. , Chen, T.H. and Lee, H.M. (2004) Celecoxib Induces Heme-Oxygenase Expression in Glomerular Mesangial Cells. Annals NY Acad Sci (in press).
18. Chao, H.T., Lee S.Y., Lee H.M., Liao, T.L., Wei, Y.H., Kao, S.H. (2004) Repeated Ovarian Stimulations Induce Oxidative Damages and Mitochondrial DNA Mutations in Mouse Ovaries. Annals N.Y. Acad. Sci. (in press).
19. Kao, S.H. , Huang, H.C., Hsieh R.H., Tsai M.C., Chen S.C., Tzeng C.R. (2004) Oxidative Damages in Endometriosis. Annals NY Acad Sci (in press).
20. Wang Y. C., Fu, R. H., Hsieh, H.J., Chao, H.T., and Kao, S.H. (2004) Polyglycolic acid/chitosan glue and apotosis of Endometriosis-derived cells. Fert Steril (revised).
21. Chao, H.T.,Lee, S.Y.,Lee H.M.,Liao, T.L., Wei, Y.H.,Kao, S.H.(2005).Repeated Ovarian Stimulations Induce Oxidative Damages and Mitochondrial DNA Mutations in Mouse Ovaries. Annals N.Y. Acad. Sci.(1042):148-156.
22. Wang Y. C.,Fu, R.H.,Hsieh, H.J.,Chao, H.T.,Kao, S.H.(2005).Polyglycolic acid/chitosan glue and apotosis of Endometriosis-derived cells. Fertil Steril.(84):75-81. 
23. Au HK, Yeh TS, Kao SH, Shih CM, Hsieh RH, Tzeng CR(2005).Calcium-dependent up-regulation of mitochondrial electron transfer chain gene expressions in human luteinized granulosa cells. Fert Steril.(84):1104-1108.
24. Au HK, Yeh TS, Kao SH, Tzeng CR, Hsieh RH(2005).Abnormal Mitochondrial Structure in Human Unfertilized Oocytes and Arrested Embryos. Annals New Yoek Acad Sci.(1042):177-185. 
25. Hou, C.C.,Hung, S.L.,Kao, S.H.,Chen, T.H.,Lee, H.M.(2005).Celecoxib Induces Heme-Oxygenase Expression in Glomerular Mesangial Cells. Annals NY Acad Sci.(1042):235-245. 
26. Kao, S.H.,Huang,H.C.,Hsieh R.H.,Tsai M.C.,Chen S.C.,Tzeng C.R.(2005).Oxidative Damages in Endometriosis. Annals NY Acad Sci.(1042):186-194. 
27. Chen TH, Hsu YT, Chen CH, Kao SH, Lee HM(2007).Tanshinone IIA from Salvia miltiorrhiza Induces Heme Oxygenase-1 Expression and Inhibits Lipopolysaccharide - Induced Nitric Oxide Expression in RAW 264.7 Cells. Mitochondrion.(7):101-105. 
28. Kao SH, Chao HT, Chen HW, Hwang TIS, Liao TL, Wei YH(2007).Oxidative stress status in sperm with declined motility. Fertil Steril (in press).():-. 
　

　

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